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Live, attenuated vaccines


A) include the Sabin polio vaccine.
B) include the measles, mumps, rubella vaccine (MMR) .
C) contain viable microbes that can multiply in the person.
D) require smaller doses and fewer boosters compared to inactivated vaccines.
E) All of these choices are correct.

F) None of the above
G) C) and D)

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Which immunoglobulin class/es can fix complement?


A) IgM only
B) IgG only
C) IgD only
D) IgM and IgG
E) IgE and IgA

F) A) and B)
G) C) and E)

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Cody is 4 months old and is given a DTaP injection by his pediatrician as part of the routine immunization schedule.What type of immunity will develop as a result of this?


A) natural active immunity
B) artificial passive immunity
C) natural passive immunity
D) artificial active immunity

E) B) and D)
F) All of the above

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All of the following are advantages of attenuated vaccines over inactivated vaccines except


A) they require smaller doses.
B) they require fewer boosters.
C) they confer longer lasting protection.
D) they can be transmitted to other people.
E) they produce infection but not disease.

F) A) and B)
G) C) and E)

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All of the following are advantages of attenuated vaccines over inactivated vaccines except


A) they confer longer lasting protection.
B) they produce infection but not disease.
C) they can mutate back to a virulent strain.
D) they require fewer boosters.
E) they require smaller doses.

F) A) and C)
G) A) and D)

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The immunoglobulin class that has a dimer form found in mucus, saliva, colostrum, and other body secretions is


A) IgA.
B) IgD.
C) IgE.
D) IgG.
E) IgM.

F) C) and E)
G) A) and E)

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Which of the following conditions have been conclusively proven to be linked to childhood vaccinations?


A) autism
B) diabetes
C) asthma
D) All of these choices are correct.

E) B) and D)
F) B) and C)

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An example of natural passive immunity would be


A) chickenpox infection is followed by lifelong immunity.
B) chickenpox vaccine triggers extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

E) A) and C)
F) C) and D)

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The process of clonal deletion is designed to


A) destroy clones of lymphocytes able to react to self molecules.
B) slow down the primary immune response to an antigen.
C) slow down the secondary immune response to an antigen.
D) limit the number of lymphocyte clones an individual has in order to make the system more efficient.
E) slow down the immune system in the elderly.

F) B) and E)
G) A) and D)

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Properties of effective antigens include all the following, except


A) foreign to the immune system.
B) molecular complexity.
C) large molecules with a minimum molecular weight of 1,000.
D) large polymers made up of identical repeating subunits.
E) cells or large, complex molecules.

F) A) and D)
G) A) and C)

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The immunoglobulin/s found on the surface of B-cells is/are


A) IgM only.
B) IgG only.
C) IgD only.
D) IgM and IgG.
E) IgE and IgA.

F) A) and B)
G) B) and E)

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An example of artificial active immunity would be


A) chickenpox infection is followed by lifelong immunity.
B) chickenpox vaccine triggers extended immunity to chickenpox.
C) giving a person immune serum globulins to chickenpox virus after exposure to the disease.
D) a fetus acquiring maternal IgG to the chickenpox virus across the placenta.

E) C) and D)
F) A) and B)

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The progeny cells of a B-cell clone are called


A) antibodies.
B) sensitized T-cells.
C) activated macrophages.
D) plasma cells.
E) Bursa cells.

F) B) and C)
G) A) and E)

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During presentation of APC-bound antigen, macrophages secrete a cytokine that activates T helper cells.What is the name of this cytokine?


A) the major histocompatibility complex
B) interleukin-2
C) IgM
D) interleukin-1

E) A) and B)
F) A) and C)

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All of the following are characteristics of IgM, except


A) it has 10 antigen binding sites.
B) it contains a central J chain.
C) it is the first class synthesized by a plasma cell.
D) it can fix complement.
E) it is a dimer.

F) B) and C)
G) A) and D)

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Which is incorrect about the Fc region of an immunoglobulin?


A) It determines the antibody's distribution in the body.
B) It forms the antigen binding sites.
C) It contains an effector molecule that can bind to cells such as macrophages and mast cells.
D) It contains an effector molecule that can fix complement.
E) It determines the class to which the immunoglobulin belongs.

F) C) and D)
G) None of the above

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When antiserum is subjected to electrophoresis, the gamma globulin band contains mostly


A) IgM.
B) IgA.
C) IgD.
D) IgE.
E) IgG.

F) B) and C)
G) B) and D)

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