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Proteins scan chromosomes for damage during the


A) G1 checkpoint.
B) beginning of the synthesis phase.
C) apoptosis phase.
D) G2 checkpoint.
E) metaphase checkpoint.

F) C) and D)
G) B) and D)

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If a cell sustains irreparable DNA damage during the S phase of the cell cycle the cell will undergo _________.

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Why would a chromosome decondense following mitosis?

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Chromosomes decondense to allo...

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If the cell does not ____________ during S phase,daughter cells may be missing some or have too many copies of certain genes.

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accurately...

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Physical side-effects from chemotherapy and radiotherapy could be maximally reduced by


A) targeting specific tumor cells.
B) reducing amounts of drug or radiation.
C) reducing exposure time.
D) better detection methods.
E) using multiple drugs with radiation.

F) A) and B)
G) C) and E)

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A specific gene,called GRAB,prevents a cell from entering mitosis if there are any signs of DNA damage.This means that GRAB would be a type of


A) cell cycle checkpoint.
B) tumor-causing gene.
C) non-hereditary gene.
D) growth signal.
E) mutation.

F) D) and E)
G) A) and D)

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Define apoptosis.Why is apoptosis important?

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Apoptosis is programmed cell d...

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If you were going to set up a clinical trial of a new chemotherapy drug that would be used in addition to traditional treatment for prostate cancer,who would you use as the control group for your experiment?


A) patients with prostate cancer who received no treatment
B) patients with prostate cancer who received traditional treatment alone
C) patients with prostate cancer who were given the trial drug but no traditional treatment
D) patients with prostate cancer who received traditional treatment plus the trial drug
E) healthy patients with no prostate cancer

F) A) and B)
G) A) and E)

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Most adults survive chemotherapy,but unborn children frequently do not.Why do you think that is? Specifically,what is the difference between an adult and an unborn child that would account for this difference?

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Most chemotherapeutic drugs inhibit cell...

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What causes cancer to kill people?


A) Cancer cells accumulate DNA mutations.
B) Tumors can spread to other parts of the body.
C) Cancer cells crowd out normal cells and disrupt organ functions.
D) Cancer cells have uncontrolled cell division.
E) Tumors cells contain abnormal DNA

F) D) and E)
G) A) and D)

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Cancer may be caused by


A) a cell cycle checkpoint problem.
B) failure in apoptosis.
C) unregulated cell division.
D) failure in DNA repair mechanisms.
E) All of the above.

F) A) and B)
G) A) and C)

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Our skin is our outermost layer,and it is exposed to all the hazards of the external environment.Thus,our skin cells are damaged on a regular basis and die.How does our body handle this frequent cell death?

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Our skin cells are replaced as...

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In drawings of chromosomes,the "X" shape indicates that


A) the DNA has been replicated.
B) two sister chromatids exist.
C) cell division hasn't yet occurred.
D) the cell is probably ready for mitosis.
E) All of the above.

F) A) and B)
G) B) and E)

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Which of the following help(s) to prevent cancer?


A) cell cycle checkpoints
B) apoptosis
C) DNA repair enzymes
D) regulation of the cell cycle
E) All of the above.

F) C) and D)
G) A) and B)

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Which of the following is NOT a stage of mitosis?


A) prophase
B) metaphase
C) interphase
D) anaphase
E) telophase

F) D) and E)
G) A) and C)

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If you cut yourself,the damaged cells are


A) sloughed off.
B) repaired by surrounding cells.
C) replaced by surrounding cells.
D) repaired by your immune system.
E) All the above.

F) A) and E)
G) B) and C)

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Sister chromatids are


A) duplicated chromosomes.
B) identical copies.
C) separated during mitosis.
D) made during the S phase.
E) All of the above.

F) B) and E)
G) A) and B)

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Explain why radiation therapy is NOT appropriate treatment for a metastasized cancer.

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Radiation is concentrated on areas conta...

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Taxol was an important new chemotherapy drug because it


A) was present in only very low amounts in tree bark.
B) killed ovarian and breast cancer cells.
C) targeted a different step of the cell cycle compared to other drugs.
D) could be extracted from widely available trees.
E) was effective and inexpensive.

F) A) and E)
G) C) and D)

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Where do cancer cells differ in their cell cycle from normal cells?

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Cancer cells seldom pause at t...

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