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Hepatitis B is usually transmitted via the oral-fecal route.

A) True
B) False

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The polymerase protein from hepatitis B virus binds to the epsiolog (e)stem-loop on the pregenomic mRNA, which is important for packaging of the genome into the capsid.

A) True
B) False

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Which of the following mechanisms is used by hepatitis B to get the viral genome packaged into the virion?


A) The polymerase interacts with both the pregenomic mRNA and the capsid protein.
B) The capsid protein interacts with the completed DNA genome.
C) The capsid is assembled around the completed DNA genome.
D) The large surface antigen interacts with the completed DNA genome.
E) The large surface antigen interacts with both the pregenomic mRNA and the capsid protein.

F) All of the above
G) C) and E)

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The longest open reading frame in the genome of hepatitis B virus genome encodes which of the proteins?


A) The E protein.
B) The X protein.
C) The largest surface antigen.
D) The capsid protein.
E) The reverse transcriptase enzyme.

F) A) and B)
G) C) and D)

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Describe the methods used to both prevent and treat hepatitis B virus (HBV)infections.

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Public health measures can be used to te...

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Which of the following occurs immediately after entry of the hepatitis B virus genome into the host cell?


A) Translation of the viral genome into proteins.
B) Integration of the viral genome into the host genome.
C) Reverse transcription of the genome into double-stranded DNA.
D) Transcription of the viral genome to make mRNAs.
E) Conversion of the genome to a covalently closed circular form.

F) A) and B)
G) None of the above

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Which of the following explains why there is a gap in the DNA genome of hepatitis B virus?


A) There is a segment of RNA that can't be removed from this region of the genome.
B) There are proteins bound to the template that block the polymerase.
C) The polymerase enzyme runs out of deoxynucleotide triphosphates.
D) The complementary strand can't base pair in this region of the genome.
E) This is where the genome integrates into the host chromosome.

F) D) and E)
G) A) and E)

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Scientists have generated mice that synthesize the X protein from hepatitis B virus in all of the liver cells.Which of the following describes the effect of the X protein on mice?


A) When infected with hepatitis B, they have a greater amount of liver damage.
B) When infected with hepatitis B, they develop a less severe liver disease.
C) They are predisposed to developing liver cancer.
D) They are resistant to infection with hepatitis B.
E) The X protein by itself can induce a hepatitis-like disease.

F) B) and C)
G) A) and D)

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