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Which of the following places these items in the correct order for DNA-virus replication? 1) Maturation 2) DNA synthesis 3) Transcription 4) Translation


A) 1;2;3;4
B) 2;3;4;1
C) 3;4;1;2
D) 4;1;2;3
E) 4;3;2;1

F) All of the above
G) C) and D)

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Viruses that utilize reverse transcriptase belong to the virus families


A) Retroviridae and Picornaviridae.
B) Herpesviridae and Retroviridae.
C) Hepadnaviridae and Retroviridae.
D) Herpesviridae and Poxviridae.
E) Rhabdoviridae and Herpesviridae.

F) A) and B)
G) B) and E)

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Which of the following is NOT used as a criterion to classify viruses?


A) biochemical tests
B) morphology
C) nucleic acid
D) size
E) number of capsomeres

F) B) and D)
G) A) and E)

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Compare and contrast the lytic cycle of infection of a DNA virus and an RNA virus.

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The lytic cycle of infection for DNA vir...

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Bacteriophages derive all of the following from the host cell EXCEPT


A) lysozyme.
B) tRNA.
C) amino acids.
D) nucleotides.
E) ATP.

F) B) and C)
G) A) and E)

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Shingles is an example of


A) reactivation of latent virus.
B) lytic virus.
C) persistent virus.
D) lysogeny.
E) transformation.

F) A) and B)
G) B) and C)

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A feature that may be found in viruses but never in bacteria is


A) the ability to pass through 0.22 micrometer pore filters.
B) may contain an RNA genome.
C) they cannot reproduce themselves outside a host.
D) a sensitivity to antibiotics.
E) an ability to infect more than one type of host.

F) A) and D)
G) B) and D)

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What contributes to antigenic shift in influenza viruses?


A) worldwide distribution of the virus
B) a segmented genome
C) attachment spikes
D) ease of virus transmission
E) different virus subtypes

F) A) and E)
G) None of the above

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Bacteriophage replication differs from animal virus replication because only bacteriophage replication involves


A) adsorption to specific receptors.
B) assembly of viral components.
C) replication of viral nucleic acid.
D) injection of naked nucleic acid into the host cell.
E) lysis of the host cell.

F) C) and D)
G) D) and E)

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Some viruses,such as human herpesvirus 1,infect a cell without causing symptoms.These are called


A) latent viruses.
B) lytic viruses.
C) phages.
D) slow viruses.
E) unconventional viruses.

F) A) and D)
G) All of the above

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________ were first identified in cancer-causing viruses and can induce ________ in infected cells.


A) Herpes viruses;lesions
B) Oncogenes;transformation
C) T antigens;lysis
D) Glycoprotein spikes;syncytia formation
E) Segmented genomes;reassortment

F) A) and B)
G) C) and D)

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Binomial nomenclature is used to name viruses.

A) True
B) False

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Oncogenic viruses


A) cause acute infections.
B) are genetically unstable.
C) cause tumors to develop.
D) are lytic viruses that kill the host cell.
E) have no effect on the host cell.

F) C) and E)
G) B) and D)

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Which of the following would be the first step in biosynthesis of a virus with a - (minus) strand of RNA?


A) synthesis of DNA from an RNA template
B) synthesis of double-stranded RNA from an RNA template
C) synthesis of double-stranded RNA from a DNA template
D) transcription of mRNA from DNA
E) synthesis of DNA from a DNA template

F) C) and D)
G) A) and E)

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Figure 13.2 Figure 13.2    -Assume a patient has influenza.During which time on the graph in Figure 13.2 would the patient show the symptoms of the illness? A) a B) b C) c D) d E) e -Assume a patient has influenza.During which time on the graph in Figure 13.2 would the patient show the symptoms of the illness?


A) a
B) b
C) c
D) d
E) e

F) A) and D)
G) D) and E)

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A viral species is a group of viruses that


A) has the same morphology and nucleic acid.
B) has the same genetic information and ecological niche.
C) infects the same cells and cause the same disease.
D) cannot be defined.

E) All of the above
F) A) and D)

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Figure 13.2 Figure 13.2    -Assume a patient had chickenpox (human herpesvirus 3) as a child.Which line on the graph in Figure 13.2 would show the number of viruses present in this person as a 60-year-old with shingles (human herpesvirus 3) ? A) a B) b C) c D) d E) e -Assume a patient had chickenpox (human herpesvirus 3) as a child.Which line on the graph in Figure 13.2 would show the number of viruses present in this person as a 60-year-old with shingles (human herpesvirus 3) ?


A) a
B) b
C) c
D) d
E) e

F) A) and B)
G) All of the above

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Continuous cell lines differ from primary cell lines in that


A) viruses can be grown in continuous cell lines.
B) continuous cell lines always have to be re-isolated from animal tissues.
C) continuous cell lines are derived from primary cell lines.
D) continuous cell lines can be maintained through an indefinite number of generations.
E) continuous cell lines are from human embryos.

F) D) and E)
G) A) and B)

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Most drugs that interfere with viral multiplication also interfere with host cell function.

A) True
B) False

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An example of a persistent viral infection is


A) Hepatitis A infection.
B) Influenza.
C) Herpes Simplex Virus infection.
D) Human Immunodeficiency Virus infection.
E) Varicellavirus infection.

F) D) and E)
G) B) and D)

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