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All of the following operate in surveillance and destruction of tumor cells, except


A) macrophages.
B) B cells.
C) natural killer cells.
D) cytotoxic T cells.

E) A) and B)
F) All of the above

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Which cells play the greatest role in allergic symptoms?


A) T-cells
B) monocytes
C) pla cells
D) mast cells
E) eosinophils

F) A) and D)
G) A) and E)

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After a bone marrow transplant, the recipient's blood type may change to the blood type of the donor.

A) True
B) False

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Which of the following is not a possible symptom of Type 1 hypersensitivity?


A) Rhinitis
B) Rashes
C) Sneezing
D) Diarrhea
E) Contact dermatitis

F) C) and D)
G) None of the above

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A female who is Rh+


A) inherited two recessive genes.
B) is in the majority of the population with regard to Rh status.
C) is at risk for a pregnancy resulting in hemolytic disease of the newborn.
D) can only have an Rh positive baby.
E) All of these choices are correct.

F) B) and D)
G) B) and C)

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Which of the following is incorrect about the role of mast cells and basophils in allergies?


A) They degranulate when triggered by a specific allergen through the IgE bound to them.
B) They carry high numbers of cell receptors that bind to IgE antibodies.
C) Their cytoplic secretory vesicles contain physiologically active cytokines.
D) They are found mainly in the lymph nodes.

E) A) and B)
F) B) and D)

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Discuss the proposed theories that attempt to explain the origin of autoimmunity.

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There are several proposed theories that...

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Any heightened or inappropriate immune response resulting in tissue damage is called a/an


A) autoimmune disease.
B) immunodeficiency.
C) hypersensitivity.
D) transfusion reaction.
E) desensitization.

F) B) and C)
G) None of the above

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Tissue transplanted from one body site on a patient to a different body site on that patient is called an _____.

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In an isograft, tissue from an identical twin is used.

A) True
B) False

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What will be the immediate action of allergen when it enters the body for a second time?


A) degranulation
B) bonding of allergen to adjacent IgE binding sites on mast cells and basophils
C) binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle.
E) Prostaglandins cause vasodilation and increased vascular permeability.

F) B) and E)
G) All of the above

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Cancer cells can not displace normal blood cells and bone marrow.

A) True
B) False

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A person with O type blood


A) lacks antibodies to A and B blood types.
B) lacks A and B antigens.
C) could not have the Rh factor.
D) is called a universal recipient.
E) All of these choices are correct.

F) C) and D)
G) B) and C)

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Which event releases the chemical mediators?


A) degranulation
B) binding of allergen to adjacent IgE binding sites on mast cells and basophils
C) binding of IgE by the Fc region to mast cells and basophils
D) Histamine acts on smooth muscle.
E) Prostaglandins cause vasodilation and increased vascular permeability.

F) C) and D)
G) All of the above

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The chemical mediator that causes prolonged bronchosp, vascular permeability, and mucus secretion of asthmatic patients is


A) prostaglandin.
B) histamine.
C) leukotriene.
D) serotonin.
E) platelet-activating factor.

F) B) and D)
G) B) and C)

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At birth, a neonate with blood Type O will have circulating anti-A and anti-B antibodies.

A) True
B) False

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All of the following are examples of autoimmune diseases, except


A) multiple sclerosis.
B) Grave's disease.
C) Hashimoto thyroiditis.
D) myasthenia gravis.
E) Wiskott-Aldrich syndrome.

F) A) and C)
G) A) and E)

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The _____ dose of an allergen results in signs and symptoms of the allergy.

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One theory regarding immune tolerance and the development of autoimmunity states that during embryonic growth, some tissues are hidden behind anatomical barriers and cannot be surveyed by the developing immune system. Later in life, some of these tissues may be exposed to the immune system as a result of trauma or infection and the immune system responds by developing an immune reaction against these tissues as if they were foreign. This theory is the


A) theory of molecular mimmicry.
B) theory of immune deficiency.
C) forbidden clone theory.
D) sequestered antigen theory.

E) None of the above
F) A) and B)

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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